SIFT dbSNP provides SIFT predictions for a list non synonymous SNPs (rsIDs) from NCBI's dbSNP (build 135) database. Either all BLAST hits can be used in the protein alignment or the top hit to each organism.

If we are unable to successfully retrieve your nsSNP from the database, please go to the SIFT homepage to see your other options.

Results are deleted after 24 hours, so please save them!

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dbSNP rsIDs
One SNP per line, starting with rs.
[Help retrieving SNPs] [Sample format] [Upload example]

Paste in rs id's


Upload file containing rsIDs

If you receive a warning that the sequences were not diverse enough for prediction on your substitution, try "all BLAST hits". If that fails, you can submit here and have SIFT find the appropriate number of sequences.